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Comparison of clinical efficacy and safety between interventional embolization and craniotomy clipping for anterior circulation aneurysms

OBJECTIVE: To investigate the clinical efficacy and safety of interventional embolization in the treatment of anterior circulation aneurysms. METHODS: Eighty patients with anterior circulation aneurysms admitted to People’s Hospital of Leshan from June 2019 to December 2021 were retrospectively anal...

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Autores principales: Lei, Bo, You, Guoliang, Wan, Xiaoqiang, Wu, Honggang, Zheng, Niandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Professional Medical Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480743/
https://www.ncbi.nlm.nih.gov/pubmed/37680817
http://dx.doi.org/10.12669/pjms.39.5.7092
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author Lei, Bo
You, Guoliang
Wan, Xiaoqiang
Wu, Honggang
Zheng, Niandong
author_facet Lei, Bo
You, Guoliang
Wan, Xiaoqiang
Wu, Honggang
Zheng, Niandong
author_sort Lei, Bo
collection PubMed
description OBJECTIVE: To investigate the clinical efficacy and safety of interventional embolization in the treatment of anterior circulation aneurysms. METHODS: Eighty patients with anterior circulation aneurysms admitted to People’s Hospital of Leshan from June 2019 to December 2021 were retrospectively analyzed. According to the different surgical methods, they were divided into two groups: the observation group and the control group. Patients in the observation group were given interventional embolization, while those in the control group were given craniotomy clipping. The surgical efficacy, postoperative neurological function and quality of life, surgical prognosis and surgical complications of the two groups were compared. RESULTS: The intraoperative blood loss and hospitalization time in the observation group were lower than those in the control group (p<0.05). The scores of the Hunt-Hess and modified Rankin scale in the observation group were significantly lower than those in the control group three months after surgery (p<0.05). The good prognosis rate of the observation group was higher than that of the control group (p<0.05). Moreover, the complication rate of the observation group was 12.50%, which was significantly lower than 32.50% in the control group (p<0.05). CONCLUSION: Interventional embolization shows the advantages of minimally invasive procedures such as shorter operative times and shorter hospital stays. It has better clinical safety because it can significantly improve the neurological function and quality of life of patients, improve the prognosis of patients, and reduce the incidence of complications.
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spelling pubmed-104807432023-09-07 Comparison of clinical efficacy and safety between interventional embolization and craniotomy clipping for anterior circulation aneurysms Lei, Bo You, Guoliang Wan, Xiaoqiang Wu, Honggang Zheng, Niandong Pak J Med Sci Original Article OBJECTIVE: To investigate the clinical efficacy and safety of interventional embolization in the treatment of anterior circulation aneurysms. METHODS: Eighty patients with anterior circulation aneurysms admitted to People’s Hospital of Leshan from June 2019 to December 2021 were retrospectively analyzed. According to the different surgical methods, they were divided into two groups: the observation group and the control group. Patients in the observation group were given interventional embolization, while those in the control group were given craniotomy clipping. The surgical efficacy, postoperative neurological function and quality of life, surgical prognosis and surgical complications of the two groups were compared. RESULTS: The intraoperative blood loss and hospitalization time in the observation group were lower than those in the control group (p<0.05). The scores of the Hunt-Hess and modified Rankin scale in the observation group were significantly lower than those in the control group three months after surgery (p<0.05). The good prognosis rate of the observation group was higher than that of the control group (p<0.05). Moreover, the complication rate of the observation group was 12.50%, which was significantly lower than 32.50% in the control group (p<0.05). CONCLUSION: Interventional embolization shows the advantages of minimally invasive procedures such as shorter operative times and shorter hospital stays. It has better clinical safety because it can significantly improve the neurological function and quality of life of patients, improve the prognosis of patients, and reduce the incidence of complications. Professional Medical Publications 2023 /pmc/articles/PMC10480743/ /pubmed/37680817 http://dx.doi.org/10.12669/pjms.39.5.7092 Text en Copyright: © Pakistan Journal of Medical Sciences https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0 (https://creativecommons.org/licenses/by/3.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lei, Bo
You, Guoliang
Wan, Xiaoqiang
Wu, Honggang
Zheng, Niandong
Comparison of clinical efficacy and safety between interventional embolization and craniotomy clipping for anterior circulation aneurysms
title Comparison of clinical efficacy and safety between interventional embolization and craniotomy clipping for anterior circulation aneurysms
title_full Comparison of clinical efficacy and safety between interventional embolization and craniotomy clipping for anterior circulation aneurysms
title_fullStr Comparison of clinical efficacy and safety between interventional embolization and craniotomy clipping for anterior circulation aneurysms
title_full_unstemmed Comparison of clinical efficacy and safety between interventional embolization and craniotomy clipping for anterior circulation aneurysms
title_short Comparison of clinical efficacy and safety between interventional embolization and craniotomy clipping for anterior circulation aneurysms
title_sort comparison of clinical efficacy and safety between interventional embolization and craniotomy clipping for anterior circulation aneurysms
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480743/
https://www.ncbi.nlm.nih.gov/pubmed/37680817
http://dx.doi.org/10.12669/pjms.39.5.7092
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