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Overexpression of CD2/CD27 could inhibit the activation of nitrogen metabolism pathways and suppress M2 polarization of macrophages, thereby preventing brain metastasis of breast cancer

OBJECTIVE: Our study aimed to reveal the possible molecular mechanisms of CD2 and CD27 in influencing the tumor microenvironment of breast cancer (BC) brain metastasis based on the TCGA (The Cancer Genome Atlas) and SRA (Sequence Read Archive) databases. METHODS: We calculated the proportions of tum...

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Detalles Bibliográficos
Autores principales:	Huang, Guanyou, Wu, Yujuan, Gan, Hongchuan, Chu, Liangzhao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480780/ https://www.ncbi.nlm.nih.gov/pubmed/37666207 http://dx.doi.org/10.1016/j.tranon.2023.101768

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