Structural insight into G-protein chaperone-mediated maturation of a bacterial adenosylcobalamin-dependent mutase

G-protein metallochaperones are essential for the proper maturation of numerous metalloenzymes. The G-protein chaperone MMAA in humans (MeaB in bacteria) uses GTP hydrolysis to facilitate the delivery of adenosylcobalamin (AdoCbl) to AdoCbl-dependent methylmalonyl-CoA mutase, an essential metabolic...

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Detalles Bibliográficos
Autores principales: Vaccaro, Francesca A., Faber, Daphne A., Andree, Gisele A., Born, David A., Kang, Gyunghoon, Fonseca, Dallas R., Jost, Marco, Drennan, Catherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481361/
https://www.ncbi.nlm.nih.gov/pubmed/37517695
http://dx.doi.org/10.1016/j.jbc.2023.105109

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