Dual role of the adhesion G-protein coupled receptor ADRGE5/CD97 in glioblastoma invasion and proliferation

CD97, an adhesion G-protein coupled receptor highly expressed in glioblastoma (GBM), consists of two noncovalently bound domains: the N-terminal fragment (NTF) and C-terminal fragment. The C-terminal fragment contains a GPCR domain that couples to Gα(12/13), while the NTF interacts with extracellula...

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Detalles Bibliográficos
Autores principales: Slepak, Tatiana I., Guyot, Manuela, Walters, Winston, Eichberg, Daniel G., Ivan, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481366/
https://www.ncbi.nlm.nih.gov/pubmed/37517698
http://dx.doi.org/10.1016/j.jbc.2023.105105

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