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Formulation and Scale-up of Delamanid Nanoparticles via Emulsification for Oral Tuberculosis Treatment

[Image: see text] Delamanid (DLM) is a hydrophobic small molecule therapeutic used to treat drug-resistant tuberculosis (DR-TB). Due to its hydrophobicity and resulting poor aqueous solubility, formulation strategies such as amorphous solid dispersions (ASDs) have been investigated to enhance its aq...

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Detalles Bibliográficos
Autores principales:	Caggiano, Nicholas J., Armstrong, Madeleine S., Georgiou, Joanna S., Rawal, Aditya, Wilson, Brian K., White, Claire E., Priestley, Rodney D., Prud’homme, Robert K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481377/ https://www.ncbi.nlm.nih.gov/pubmed/37578286 http://dx.doi.org/10.1021/acs.molpharmaceut.3c00240

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