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Improvement of the Effectiveness of HER2+ Cancer Therapy by Use of Doxorubicin and Trastuzumab Modified Radioactive Gold Nanoparticles

[Image: see text] In the present article, we describe a multimodal radiobioconjugate that contains a chemotherapeutic agent (doxorubicin, DOX), a β-emitter ((198)Au), and a guiding vector (trastuzumab, Tmab) for targeted therapy of cancers overexpressing HER2 receptors. To achieve this goal, radioac...

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Detalles Bibliográficos
Autores principales:	Żelechowska-Matysiak, Kinga, Salvanou, Evangelia-Alexandra, Bouziotis, Penelope, Budlewski, Tadeusz, Bilewicz, Aleksander, Majkowska-Pilip, Agnieszka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481397/ https://www.ncbi.nlm.nih.gov/pubmed/37607353 http://dx.doi.org/10.1021/acs.molpharmaceut.3c00414

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