Reduced expression of phosphorylated ataxia-telangiectasia mutated gene is related to poor prognosis and gemcitabine chemoresistance in pancreatic cancer

BACKGROUND: Loss of expression of the gene ataxia-telangiectasia mutated (ATM), occurring in patients with multiple primary malignancies, including pancreatic cancer, is associated with poor prognosis. In this study, we investigated the detailed molecular mechanism through which ATM expression affec...

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Detalles Bibliográficos
Autores principales: Xun, Jingyu, Ohtsuka, Hideo, Hirose, Katsuya, Douchi, Daisuke, Nakayama, Shun, Ishida, Masaharu, Miura, Takayuki, Ariake, Kyohei, Mizuma, Masamichi, Nakagawa, Kei, Morikawa, Takanori, Furukawa, Toru, Unno, Michiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481509/
https://www.ncbi.nlm.nih.gov/pubmed/37674118
http://dx.doi.org/10.1186/s12885-023-11294-3

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