Activation, but not inhibition, of the indirect pathway disrupts choice rejection in a freely moving, multiple-choice foraging task

The dorsomedial striatum (DMS) plays a key role in action selection, but less is known about how direct and indirect pathway spiny projection neurons (dSPNs and iSPNs, respectively) contribute to choice rejection in freely moving animals. Here, we use pathway-specific chemogenetic manipulation durin...

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Detalles Bibliográficos
Autores principales: Delevich, Kristen, Hoshal, Benjamin, Zhou, Lexi Z., Zhang, Yuting, Vedula, Satya, Lin, Wan Chen, Chase, Juliana, Collins, Anne G.E., Wilbrecht, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481643/
https://www.ncbi.nlm.nih.gov/pubmed/35905722
http://dx.doi.org/10.1016/j.celrep.2022.111129

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