The adaptive roles of aneuploidy and polyclonality in Leishmania in response to environmental stress

Aneuploidy is generally considered harmful, but in some microorganisms, it can act as an adaptive mechanism against environmental stress. Here, we use Leishmania—a protozoan parasite with remarkable genome plasticity—to study the early steps of aneuploidy evolution under high drug pressure (using an...

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Detalles Bibliográficos
Autores principales: Negreira, Gabriel H, de Groote, Robin, Van Giel, Dorien, Monsieurs, Pieter, Maes, Ilse, de Muylder, Geraldine, Van den Broeck, Frederik, Dujardin, Jean‐Claude, Domagalska, Malgorzata A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481652/
https://www.ncbi.nlm.nih.gov/pubmed/37470283
http://dx.doi.org/10.15252/embr.202357413

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