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Evaluation of the mechanical properties and clinical application of nickel–titanium shape memory alloy anal fistula clip

OBJECTIVE: The study investigates the mechanical properties of a nickel–titanium shape memory alloy anal fistula clip (NiTi-AFC), studies the surgical method of treating anal fistula, and evaluates its clinical efficacy. METHODS: The anal fistula clip was formed in nickel–titanium alloy with a titan...

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Autores principales: Deng, Heng, Li, Ming, Fang, Xiaoli, Zhang, Jun, Wang, Jianmin, Tang, Kun, Tang, Ran, Jia, Ru, Han, Ying, Shi, Yang, Dong, Yu'ang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481869/
https://www.ncbi.nlm.nih.gov/pubmed/37680263
http://dx.doi.org/10.3389/fsurg.2023.1235666
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author Deng, Heng
Li, Ming
Fang, Xiaoli
Zhang, Jun
Wang, Jianmin
Tang, Kun
Tang, Ran
Jia, Ru
Han, Ying
Shi, Yang
Dong, Yu'ang
author_facet Deng, Heng
Li, Ming
Fang, Xiaoli
Zhang, Jun
Wang, Jianmin
Tang, Kun
Tang, Ran
Jia, Ru
Han, Ying
Shi, Yang
Dong, Yu'ang
author_sort Deng, Heng
collection PubMed
description OBJECTIVE: The study investigates the mechanical properties of a nickel–titanium shape memory alloy anal fistula clip (NiTi-AFC), studies the surgical method of treating anal fistula, and evaluates its clinical efficacy. METHODS: The anal fistula clip was formed in nickel–titanium alloy with a titanium content of 50.0%–51.8%. The mechanical properties and chemical properties were tested. A total of 31 patients with anal fistula were enrolled between 1 January 2020 and 1 January 2023. All patients underwent internal orifice closure surgery using NiTi-AFC, and anorectal magnetic resonance or ultrasound was performed before surgery and 6 months after surgery for diagnosis and evaluation. Fistula cure rates, length of stay, perianal pain, and Wexner incontinence scores were retrospectively compared between patients treated with NiTi-AFC and patients treated with other surgical methods. RESULT: NiTi-AFC has a density of 6.44–6.50 g·cm(−3), with a shape-restoring force of 63.8 N. The corrosion rate of NiTi-AFC in 0.05% hydrochloric acid solution at atmospheric pressure and 20°C is approximately 6.8 × 10(−5) g·(m·h)(−1). A total of 31 patients (male/female: 19/12, age: 43.7 ± 17.8 years) were included. Among them, 22.6% (7) had multiple anal fistula, 16.1% (5) had high anal fistula, and 48.3% (15) had perianal fistula Crohn's disease. In total, 12.9% (4/31) did not achieve primary healing, underwent fistula resection, and eventually recovered. A retrospective analysis showed that the fistula healing rate, length of stay, and anal pain of NiTi-AFC treatment were similar to those of other traditional surgeries, but the Wexner incontinence score was significantly lower. CONCLUSION: NiTi-AFC has shape memory properties, corrosion resistance, superelastic effect, and surface cell adhesion. It is applied to internal orifice closure surgery of anal fistula, with good therapeutic effect, and can protect the anal function.
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spelling pubmed-104818692023-09-07 Evaluation of the mechanical properties and clinical application of nickel–titanium shape memory alloy anal fistula clip Deng, Heng Li, Ming Fang, Xiaoli Zhang, Jun Wang, Jianmin Tang, Kun Tang, Ran Jia, Ru Han, Ying Shi, Yang Dong, Yu'ang Front Surg Surgery OBJECTIVE: The study investigates the mechanical properties of a nickel–titanium shape memory alloy anal fistula clip (NiTi-AFC), studies the surgical method of treating anal fistula, and evaluates its clinical efficacy. METHODS: The anal fistula clip was formed in nickel–titanium alloy with a titanium content of 50.0%–51.8%. The mechanical properties and chemical properties were tested. A total of 31 patients with anal fistula were enrolled between 1 January 2020 and 1 January 2023. All patients underwent internal orifice closure surgery using NiTi-AFC, and anorectal magnetic resonance or ultrasound was performed before surgery and 6 months after surgery for diagnosis and evaluation. Fistula cure rates, length of stay, perianal pain, and Wexner incontinence scores were retrospectively compared between patients treated with NiTi-AFC and patients treated with other surgical methods. RESULT: NiTi-AFC has a density of 6.44–6.50 g·cm(−3), with a shape-restoring force of 63.8 N. The corrosion rate of NiTi-AFC in 0.05% hydrochloric acid solution at atmospheric pressure and 20°C is approximately 6.8 × 10(−5) g·(m·h)(−1). A total of 31 patients (male/female: 19/12, age: 43.7 ± 17.8 years) were included. Among them, 22.6% (7) had multiple anal fistula, 16.1% (5) had high anal fistula, and 48.3% (15) had perianal fistula Crohn's disease. In total, 12.9% (4/31) did not achieve primary healing, underwent fistula resection, and eventually recovered. A retrospective analysis showed that the fistula healing rate, length of stay, and anal pain of NiTi-AFC treatment were similar to those of other traditional surgeries, but the Wexner incontinence score was significantly lower. CONCLUSION: NiTi-AFC has shape memory properties, corrosion resistance, superelastic effect, and surface cell adhesion. It is applied to internal orifice closure surgery of anal fistula, with good therapeutic effect, and can protect the anal function. Frontiers Media S.A. 2023-08-23 /pmc/articles/PMC10481869/ /pubmed/37680263 http://dx.doi.org/10.3389/fsurg.2023.1235666 Text en © 2023 Deng, Li, Fang, Zhang, Wang, Tang, Tang, Jia, Han, Shi and Dong. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Deng, Heng
Li, Ming
Fang, Xiaoli
Zhang, Jun
Wang, Jianmin
Tang, Kun
Tang, Ran
Jia, Ru
Han, Ying
Shi, Yang
Dong, Yu'ang
Evaluation of the mechanical properties and clinical application of nickel–titanium shape memory alloy anal fistula clip
title Evaluation of the mechanical properties and clinical application of nickel–titanium shape memory alloy anal fistula clip
title_full Evaluation of the mechanical properties and clinical application of nickel–titanium shape memory alloy anal fistula clip
title_fullStr Evaluation of the mechanical properties and clinical application of nickel–titanium shape memory alloy anal fistula clip
title_full_unstemmed Evaluation of the mechanical properties and clinical application of nickel–titanium shape memory alloy anal fistula clip
title_short Evaluation of the mechanical properties and clinical application of nickel–titanium shape memory alloy anal fistula clip
title_sort evaluation of the mechanical properties and clinical application of nickel–titanium shape memory alloy anal fistula clip
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481869/
https://www.ncbi.nlm.nih.gov/pubmed/37680263
http://dx.doi.org/10.3389/fsurg.2023.1235666
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