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The influence of variable-heavy chain families on IgG(2), (3), (4), FcγRs and B-cell superantigens protein G and L binding using biolayer interferometry
As the most abundant immunoglobulin in blood and the most common human isotype used for therapeutic monoclonal antibodies, the engagement and activation of its Fc receptors by IgGs are crucial for antibody function. Assumed to be relatively constant within subtypes, recent studies reveal that antibo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481891/ https://www.ncbi.nlm.nih.gov/pubmed/37680351 http://dx.doi.org/10.1093/abt/tbad016 |