Cargando…

Circulating Tumor DNA as a Prognostic Factor in Patients With Resectable Hepatic Metastases of Uveal Melanoma

OBJECTIVE: We report here the results of a prospective study of circulating tumor DNA (ctDNA) detection in patients undergoing uveal melanoma (UM) liver metastases resection (NCT02849145). BACKGROUND: In UM patients, the liver is the most common and often only site of metastases. Local treatments of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mariani, Pascale, Bidard, François-Clément, Rampanou, Aurore, Houy, Alexandre, Servois, Vincent, Ramtohul, Toulsie, Pierron, Gaelle, Chevrier, Marion, Renouf, Benjamin, Lantz, Olivier, Gardrat, Sophie, Vincent-Salomon, Anne, Roman-Roman, Sergio, Rodrigues, Manuel, Piperno-Neumann, Sophie, Cassoux, Nathalie, Stern, Marc-Henri, Renault, Shufang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481917/ https://www.ncbi.nlm.nih.gov/pubmed/36847256 http://dx.doi.org/10.1097/SLA.0000000000005822

Ejemplares similares

Prognostic Implications of MRI Melanin Quantification and Cytogenetic Abnormalities in Liver Metastases of Uveal Melanoma
por: Ramtohul, Toulsie, et al.
Publicado: (2021)

Outlier response to anti-PD1 in uveal melanoma reveals germline MBD4 mutations in hypermutated tumors
por: Rodrigues, Manuel, et al.
Publicado: (2018)

Nivolumab plus ipilimumab in metastatic uveal melanoma: a real-life, retrospective cohort of 47 patients
por: Salaün, Hélène, et al.
Publicado: (2022)

Replacement and desmoplastic histopathological growth patterns: A pilot study of prediction of outcome in patients with uveal melanoma liver metastases
por: Barnhill, Raymond, et al.
Publicado: (2018)

Upcoming translational challenges for uveal melanoma
por: Nabil, Amirouchene-Angelozzi, et al.
Publicado: (2015)

Upcoming translational challenges for uveal melanoma
por: Amirouchene-Angelozzi, Nabil, et al.
Publicado: (2015)

Phase II Trial of Bevacizumab in Combination With Temozolomide as First-Line Treatment in Patients With Metastatic Uveal Melanoma
por: Piperno-Neumann, Sophie, et al.
Publicado: (2016)

Germline MBD4 Mutations and Predisposition to Uveal Melanoma
por: Derrien, Anne-Céline, et al.
Publicado: (2020)

Pretreatment Tumor Growth Rate and Radiological Response as Predictive Markers of Pathological Response and Survival in Patients with Resectable Lung Cancer Treated by Neoadjuvant Treatment
por: Ramtohul, Toulsie, et al.
Publicado: (2023)

FAK Inhibitor-Based Combinations with MEK or PKC Inhibitors Trigger Synergistic Antitumor Effects in Uveal Melanoma
por: Tarin, Malcy, et al.
Publicado: (2023)

Development of a Prognostic Nomogram for Liver Metastasis of Uveal Melanoma Patients Selected by Liver MRI
por: Mariani, Pascale, et al.
Publicado: (2019)

Patient Derived Xenografts (PDX) Models as an Avatar to Assess Personalized Therapy Options in Uveal Melanoma: A Feasibility Study
por: Nemati, Fariba, et al.
Publicado: (2023)

Prospective validation in epithelial tumors of a gene expression predictor of liver metastasis derived from uveal melanoma
por: Tsantoulis, Petros, et al.
Publicado: (2019)

Cytidine analogs are synthetic lethal with base excision repair default due to MBD4 deficiency
por: Chabot, Thomas, et al.
Publicado: (2022)

The Prognostic Values of PARP-1 Expression in Uveal Melanoma
por: Gajdzis, Malgorzata, et al.
Publicado: (2021)

Quantitative CT Extent of Lung Damage in COVID-19 Pneumonia Is an Independent Risk Factor for Inpatient Mortality in a Population of Cancer Patients: A Prospective Study
por: Ramtohul, Toulsie, et al.
Publicado: (2020)

Definition of Biologically Distinct Groups of Conjunctival Melanomas According to Etiological Factors and Implications for Precision Medicine
por: Gardrat, Sophie, et al.
Publicado: (2021)

Ephrin Receptors (Eph): EphA1, EphA5, and EphA7 Expression in Uveal Melanoma—Associations with Clinical Parameters and Patient Survival
por: Gajdzis, Malgorzata, et al.
Publicado: (2020)

Different Pigmentation Risk Loci for High-Risk Monosomy 3 and Low-Risk Disomy 3 Uveal Melanomas
por: Mobuchon, Lenha, et al.
Publicado: (2021)

PARP Inhibition Increases the Response to Chemotherapy in Uveal Melanoma
por: de Koning, Leanne, et al.
Publicado: (2019)

Characteristics and Outcome of SARS-CoV-2 Infection in Cancer Patients
por: Basse, Clémence, et al.
Publicado: (2021)

Selumetinib-based therapy in uveal melanoma patient-derived xenografts
por: Decaudin, Didier, et al.
Publicado: (2018)

Histone Deacetylase (HDAC)-1, -2, -4, and -6 in Uveal Melanomas: Associations with Clinicopathological Parameters and Patients’ Survival
por: Levidou, Georgia, et al.
Publicado: (2021)

EPHA2, EPHA4, and EPHA6 Expression in Uveal Melanomas: Searching for the Culprits of Neoplasia
por: Pergaris, Alexandros, et al.
Publicado: (2022)

COVID-19 in breast cancer patients: a cohort at the Institut Curie hospitals in the Paris area
por: Vuagnat, Perrine, et al.
Publicado: (2020)

So Close, yet so Far: Discrepancies between Uveal and Other Melanomas. A Position Paper from UM Cure 2020
por: Rodrigues, Manuel, et al.
Publicado: (2019)

Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma
por: Carita, Guillaume, et al.
Publicado: (2016)

Multi-omics comparison of malignant and normal uveal melanocytes reveals molecular features of uveal melanoma
por: Gentien, David, et al.
Publicado: (2023)

Genome-wide profiling is a clinically relevant and affordable prognostic test in posterior uveal melanoma
por: Cassoux, Nathalie, et al.
Publicado: (2014)

A GWAS in uveal melanoma identifies risk polymorphisms in the CLPTM1L locus
por: Mobuchon, Lenha, et al.
Publicado: (2017)

Prognostic factors of successful on-purpose tumor biopsies in metastatic cancer patients included in the SHIVA prospective clinical trial
por: Desportes, Emilie, et al.
Publicado: (2016)

Angiotropism and extravascular migratory metastasis in cutaneous and uveal melanoma progression in a zebrafish model
por: Fornabaio, Giulia, et al.
Publicado: (2018)

Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage
por: Alsafadi, Samar, et al.
Publicado: (2016)

Glycolysis Dependency as a Hallmark of SF3B1-Mutated Cells
por: Vivet-Noguer, Raquel, et al.
Publicado: (2022)

Breast carcinomas with osteoclast-like giant cells: a comprehensive clinico-pathological and molecular portrait and evidence of RANK-L expression
por: Cyrta, Joanna, et al.
Publicado: (2022)

Relevance of a molecular tumour board (MTB) for patients’ enrolment in clinical trials: experience of the Institut Curie
por: Basse, Clémence, et al.
Publicado: (2018)

ShallowHRD: detection of homologous recombination deficiency from shallow whole genome sequencing
por: Eeckhoutte, Alexandre, et al.
Publicado: (2020)

Functional characterization of 5p15.33 risk locus in uveal melanoma reveals rs452384 as a functional variant and NKX2.4 as an allele-specific interactor
por: Derrien, Anne-Céline, et al.
Publicado: (2022)

Sorafenib in metastatic uveal melanoma: efficacy, toxicity and health-related quality of life in a multicentre phase II study
por: Mouriaux, F, et al.
Publicado: (2016)

A novel combinatorial treatment option for metastatic uveal melanoma
por: Shneor, Dudi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_d9fcjqh4g9q27su9e5oakhp66d