Obesity exacerbates influenza-induced respiratory disease via the arachidonic acid-p38 MAPK pathway

Obesity is a risk factor for severe influenza, and asthma exacerbations caused by respiratory viral infections. We investigated mechanisms that increase the severity of airway disease related to influenza in obesity using cells derived from obese and lean individuals, and in vitro and in vivo models...

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Detalles Bibliográficos
Autores principales: Chandrasekaran, Ravishankar, Morris, Carolyn R., Butzirus, Isabella M., Mark, Zoe F., Kumar, Amit, Souza De Lima, Dhemerson, Daphtary, Nirav, Aliyeva, Minara, Poynter, Matthew E., Anathy, Vikas, Dixon, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482034/
https://www.ncbi.nlm.nih.gov/pubmed/37680710
http://dx.doi.org/10.3389/fphar.2023.1248873

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