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A Case of Liquorice-Infused Marijuana Causing Syndrome of Apparent Mineralocorticoid Excess

Marijuana has long been used both for recreational and medicinal purposes. Most of the available forms of marijuana contain additives such as liquorice to enhance its flavour. Liquorice increases the amounts of cortisol in the body and produces metabolic abnormalities seen in primary hyperaldosteron...

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Detalles Bibliográficos
Autores principales: Latif, Asnia, Naqi, Muniba, McAnally, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482139/
https://www.ncbi.nlm.nih.gov/pubmed/37680778
http://dx.doi.org/10.12890/2023_003991
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author Latif, Asnia
Naqi, Muniba
McAnally, James F.
author_facet Latif, Asnia
Naqi, Muniba
McAnally, James F.
author_sort Latif, Asnia
collection PubMed
description Marijuana has long been used both for recreational and medicinal purposes. Most of the available forms of marijuana contain additives such as liquorice to enhance its flavour. Liquorice increases the amounts of cortisol in the body and produces metabolic abnormalities seen in primary hyperaldosteronism([1]). Liquorice extracts are mixed with marijuana in the same way as for tobacco([2,3]). We describe a case of apparent mineralocorticoid excess due to excessive smoking of liquorice-laced marijuana. To our knowledge, this is the first reported case of apparent mineralocorticoid excess caused by marijuana use. LEARNING POINTS: First report of liquorice-laced marijuana causing syndrome of apparent mineralocorticoid excess (SAME). Since its legalisation, marijuana is reported to be the most used substance second only to alcohol. With the increased availability of marijuana, the health care providers and consumers must be cognisant of its side effects. It is a dose-dependent phenomenon. The effects vary from minor clinical symptoms to fatal arrhythmias based on the amount consumed.
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spelling pubmed-104821392023-09-07 A Case of Liquorice-Infused Marijuana Causing Syndrome of Apparent Mineralocorticoid Excess Latif, Asnia Naqi, Muniba McAnally, James F. Eur J Case Rep Intern Med Article Marijuana has long been used both for recreational and medicinal purposes. Most of the available forms of marijuana contain additives such as liquorice to enhance its flavour. Liquorice increases the amounts of cortisol in the body and produces metabolic abnormalities seen in primary hyperaldosteronism([1]). Liquorice extracts are mixed with marijuana in the same way as for tobacco([2,3]). We describe a case of apparent mineralocorticoid excess due to excessive smoking of liquorice-laced marijuana. To our knowledge, this is the first reported case of apparent mineralocorticoid excess caused by marijuana use. LEARNING POINTS: First report of liquorice-laced marijuana causing syndrome of apparent mineralocorticoid excess (SAME). Since its legalisation, marijuana is reported to be the most used substance second only to alcohol. With the increased availability of marijuana, the health care providers and consumers must be cognisant of its side effects. It is a dose-dependent phenomenon. The effects vary from minor clinical symptoms to fatal arrhythmias based on the amount consumed. SMC Media Srl 2023-08-21 /pmc/articles/PMC10482139/ /pubmed/37680778 http://dx.doi.org/10.12890/2023_003991 Text en © EFIM 2023 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Article
Latif, Asnia
Naqi, Muniba
McAnally, James F.
A Case of Liquorice-Infused Marijuana Causing Syndrome of Apparent Mineralocorticoid Excess
title A Case of Liquorice-Infused Marijuana Causing Syndrome of Apparent Mineralocorticoid Excess
title_full A Case of Liquorice-Infused Marijuana Causing Syndrome of Apparent Mineralocorticoid Excess
title_fullStr A Case of Liquorice-Infused Marijuana Causing Syndrome of Apparent Mineralocorticoid Excess
title_full_unstemmed A Case of Liquorice-Infused Marijuana Causing Syndrome of Apparent Mineralocorticoid Excess
title_short A Case of Liquorice-Infused Marijuana Causing Syndrome of Apparent Mineralocorticoid Excess
title_sort case of liquorice-infused marijuana causing syndrome of apparent mineralocorticoid excess
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482139/
https://www.ncbi.nlm.nih.gov/pubmed/37680778
http://dx.doi.org/10.12890/2023_003991
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