HIV-1 Vpr induces ciTRAN to prevent transcriptional repression of the provirus

The functional consequences of circular RNA (circRNA) expression on HIV-1 replication are largely unknown. Using a customized protocol involving direct RNA nanopore sequencing, here, we captured circRNAs from HIV-1–infected T cells and identified ciTRAN, a circRNA that modulates HIV-1 transcription....

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Detalles Bibliográficos
Autores principales: Bhardwaj, Vipin, Singh, Aman, Choudhary, Aditi, Dalavi, Rishikesh, Ralte, Lalchhanhima, Chawngthu, Richard L., Senthil Kumar, Nachimuthu, Vijay, Nagarjun, Chande, Ajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482341/
https://www.ncbi.nlm.nih.gov/pubmed/37672576
http://dx.doi.org/10.1126/sciadv.adh9170

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