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Shigella induces epigenetic reprogramming of zebrafish neutrophils

Trained immunity is a long-term memory of innate immune cells, generating an improved response upon reinfection. Shigella is an important human pathogen and inflammatory paradigm for which there is no effective vaccine. Using zebrafish larvae, we demonstrate that after Shigella training, neutrophils...

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Detalles Bibliográficos
Autores principales: Gomes, Margarida C., Brokatzky, Dominik, Bielecka, Magdalena K., Wardle, Fiona C., Mostowy, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482349/
https://www.ncbi.nlm.nih.gov/pubmed/37672585
http://dx.doi.org/10.1126/sciadv.adf9706