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Bidirectional multiciliated cell extrusion is controlled by Notch-driven basal extrusion and Piezo1-driven apical extrusion
Xenopus embryos are covered with a complex epithelium containing numerous multiciliated cells (MCCs). During late-stage development, there is a dramatic remodeling of the epithelium that involves the complete loss of MCCs. Cell extrusion is a well-characterized process for driving cell loss while ma...
Autores principales: | Ventrella, Rosa, Kim, Sun K., Sheridan, Jennifer, Grata, Aline, Bresteau, Enzo, Hassan, Osama A., Suva, Eve E., Walentek, Peter, Mitchell, Brian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482390/ https://www.ncbi.nlm.nih.gov/pubmed/37602491 http://dx.doi.org/10.1242/dev.201612 |
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