Bidirectional multiciliated cell extrusion is controlled by Notch-driven basal extrusion and Piezo1-driven apical extrusion

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Xenopus embryos are covered with a complex epithelium containing numerous multiciliated cells (MCCs). During late-stage development, there is a dramatic remodeling of the epithelium that involves the complete loss of MCCs. Cell extrusion is a well-characterized process for driving cell loss while ma...

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Detalles Bibliográficos
Autores principales: Ventrella, Rosa, Kim, Sun K., Sheridan, Jennifer, Grata, Aline, Bresteau, Enzo, Hassan, Osama A., Suva, Eve E., Walentek, Peter, Mitchell, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482390/
https://www.ncbi.nlm.nih.gov/pubmed/37602491
http://dx.doi.org/10.1242/dev.201612
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