AP2α negatively regulates PDHA1 in cervical cancer cells to promote aggressive features and aerobic glycolysis in vitro and in vivo

OBJECTIVE: As a gate-keeper enzyme link, pyruvate dehydrogenase E1 subunit alpha (PDHA1) functions as a key regulator during glycolysis and the mitochondrial citric acid cycle, which has been reported in several tumors. Nevertheless, the effects of PDHA1 on biological behaviors and metabolism remain...

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Detalles Bibliográficos
Autores principales: Zhao, Lijie, Geng, Rong, Huang, Yi, Zhang, Jiping, Cheng, Haiying, Zhou, Cankun, Wang, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482590/
https://www.ncbi.nlm.nih.gov/pubmed/37055163
http://dx.doi.org/10.3802/jgo.2023.34.e59

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