SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks

Joint profiling of chromatin accessibility and gene expression in individual cells provides an opportunity to decipher enhancer-driven gene regulatory networks (GRNs). Here we present a method for the inference of enhancer-driven GRNs, called SCENIC+. SCENIC+ predicts genomic enhancers along with ca...

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Detalles Bibliográficos
Autores principales: Bravo González-Blas, Carmen, De Winter, Seppe, Hulselmans, Gert, Hecker, Nikolai, Matetovici, Irina, Christiaens, Valerie, Poovathingal, Suresh, Wouters, Jasper, Aibar, Sara, Aerts, Stein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482700/
https://www.ncbi.nlm.nih.gov/pubmed/37443338
http://dx.doi.org/10.1038/s41592-023-01938-4

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