Bacteroides Fragilis in the gut microbiomes of Alzheimer’s disease activates microglia and triggers pathogenesis in neuronal C/EBPβ transgenic mice

Gut dysbiosis contributes to Alzheimer’s disease (AD) pathogenesis, and Bacteroides strains are selectively elevated in AD gut microbiota. However, it remains unknown which Bacteroides species and how their metabolites trigger AD pathologies. Here we show that Bacteroides fragilis and their metaboli...

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Detalles Bibliográficos
Autores principales: Xia, Yiyuan, Xiao, Yifan, Wang, Zhi-Hao, Liu, Xia, Alam, Ashfaqul M., Haran, John P., McCormick, Beth A., Shu, Xiji, Wang, Xiaochuan, Ye, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482867/
https://www.ncbi.nlm.nih.gov/pubmed/37673907
http://dx.doi.org/10.1038/s41467-023-41283-w

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