FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1

Regenerative therapy based on mesenchymal stem cells (MSCs) has great promise to achieve functional recovery in cerebral infarction patients. However, the survival rate of transplanted MSCs is extremely low because of destructive autophagy caused by the harsh ischemic microenvironment in cerebral in...

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Detalles Bibliográficos
Autores principales: Wei, Huan, Liu, Shuaiye, Wang, Tingting, Li, Yanping, Liu, Kangmei, Guo, Qunying, Li, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482879/
https://www.ncbi.nlm.nih.gov/pubmed/37673870
http://dx.doi.org/10.1038/s41420-023-01634-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482879/
https://www.ncbi.nlm.nih.gov/pubmed/37673870
http://dx.doi.org/10.1038/s41420-023-01634-4

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