Apolipoprotein A-I vascular gene therapy reduces vein-graft atherosclerosis

Coronary artery venous bypass grafts typically fail because of atherosclerosis driven by lipid and macrophage accumulation. Therapy for vein-graft atherosclerosis is limited to statin drugs, which are only modestly effective. We hypothesized that transduction of vein-graft endothelium of fat-fed rab...

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Detalles Bibliográficos
Autores principales: Bi, Lianxiang, Wacker, Bradley K., Komandur, Kaushik, Sanford, Nicole, Dichek, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482902/
https://www.ncbi.nlm.nih.gov/pubmed/37693942
http://dx.doi.org/10.1016/j.omtm.2023.08.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482902/
https://www.ncbi.nlm.nih.gov/pubmed/37693942
http://dx.doi.org/10.1016/j.omtm.2023.08.018

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