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Apolipoprotein A-I vascular gene therapy reduces vein-graft atherosclerosis
Coronary artery venous bypass grafts typically fail because of atherosclerosis driven by lipid and macrophage accumulation. Therapy for vein-graft atherosclerosis is limited to statin drugs, which are only modestly effective. We hypothesized that transduction of vein-graft endothelium of fat-fed rab...
Autores principales: | Bi, Lianxiang, Wacker, Bradley K., Komandur, Kaushik, Sanford, Nicole, Dichek, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482902/ https://www.ncbi.nlm.nih.gov/pubmed/37693942 http://dx.doi.org/10.1016/j.omtm.2023.08.018 |
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