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Hornerin mediates phosphorylation of the polo-box domain in Plk1 by Chk1 to induce death in mitosis

The centrosome assembles a bipolar spindle for faithful chromosome segregation during mitosis. To prevent the inheritance of DNA damage, the DNA damage response (DDR) triggers programmed spindle multipolarity and concomitant death in mitosis through a poorly understood mechanism. We identified horne...

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Detalles Bibliográficos
Autores principales:	Song, Haiyu, Kim, Eun Ho, Hong, Jihee, Gwon, Dasom, Kim, Jee Won, Bae, Gyu-Un, Jang, Chang-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482915/ https://www.ncbi.nlm.nih.gov/pubmed/37596441 http://dx.doi.org/10.1038/s41418-023-01208-y

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