Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression

Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by central nervous (CNS) demyelination resulting in axonal injury and neurological deficits. Essentially, MS is driven by an auto-amplifying mechanism of inflammation and cell death. Current therapies mainly focus on disease modi...

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Detalles Bibliográficos
Autores principales: Van San, Emily, Debruyne, Angela C., Veeckmans, Geraldine, Tyurina, Yulia Y., Tyurin, Vladimir A., Zheng, Hao, Choi, Sze Men, Augustyns, Koen, van Loo, Geert, Michalke, Bernhard, Venkataramani, Vivek, Toyokuni, Shinya, Bayir, Hülya, Vandenabeele, Peter, Hassannia, Behrouz, Vanden Berghe, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482919/
https://www.ncbi.nlm.nih.gov/pubmed/37542104
http://dx.doi.org/10.1038/s41418-023-01195-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482919/
https://www.ncbi.nlm.nih.gov/pubmed/37542104
http://dx.doi.org/10.1038/s41418-023-01195-0

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