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Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by central nervous (CNS) demyelination resulting in axonal injury and neurological deficits. Essentially, MS is driven by an auto-amplifying mechanism of inflammation and cell death. Current therapies mainly focus on disease modi...
Autores principales: | Van San, Emily, Debruyne, Angela C., Veeckmans, Geraldine, Tyurina, Yulia Y., Tyurin, Vladimir A., Zheng, Hao, Choi, Sze Men, Augustyns, Koen, van Loo, Geert, Michalke, Bernhard, Venkataramani, Vivek, Toyokuni, Shinya, Bayir, Hülya, Vandenabeele, Peter, Hassannia, Behrouz, Vanden Berghe, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482919/ https://www.ncbi.nlm.nih.gov/pubmed/37542104 http://dx.doi.org/10.1038/s41418-023-01195-0 |
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