Tranexamic acid in a mouse model of cerebral amyloid angiopathy: setting the stage for a novel stroke treatment approach

BACKGROUND: Symptomatic intracerebral hemorrhage (sICH) commonly occurs in patients with cerebral amyloid angiopathy (CAA). Amyloid also initiates plasminogen activation and might promote sICH. OBJECTIVES: As amyloid-driven plasmin formation can be blocked by tranexamic acid (TXA), we aimed to evalu...

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Detalles Bibliográficos
Autores principales: Liu, Zikou, McCutcheon, Fiona M., Ho, Heidi, Chia, Joanne, Xiao, Yunxin, Tippett, Isabel, Keragala, Charithani B., Cloud, Geoffrey C., Medcalf, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483050/
https://www.ncbi.nlm.nih.gov/pubmed/37694270
http://dx.doi.org/10.1016/j.rpth.2023.102166

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