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URAT1 is expressed in cardiomyocytes and dotinurad attenuates the development of diet-induced metabolic heart disease

We recently reported that the selective inhibition of urate transporter-1 (URAT1), which is primarily expressed in the kidneys, ameliorates insulin resistance by attenuating hepatic steatosis and improving brown adipose tissue function in diet-induced obesity. In this study, we evaluated the effects...

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Detalles Bibliográficos
Autores principales: Tanaka, Yoshiro, Nagoshi, Tomohisa, Takahashi, Hirotake, Oi, Yuhei, Yasutake, Rei, Yoshii, Akira, Kimura, Haruka, Kashiwagi, Yusuke, Tanaka, Toshikazu D., Shimoda, Masayuki, Yoshimura, Michihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483053/
https://www.ncbi.nlm.nih.gov/pubmed/37694143
http://dx.doi.org/10.1016/j.isci.2023.107730