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Long-term survival of LGR5 expressing supporting cells after severe ototoxic trauma in the adult mouse cochlea
INTRODUCTION: The leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) is a tissue resident stem cell marker, which it is expressed in supporting cells (SCs) in the organ of Corti in the mammalian inner ear. These LGR5+ SCs can be used as an endogenous source of progenitor cells for re...
Autores principales: | Smith-Cortinez, Natalia, Hendriksen, Ferry G. J., Ramekers, Dyan, Stokroos, Robert J., Versnel, Huib, Straatman, Louise V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483136/ https://www.ncbi.nlm.nih.gov/pubmed/37692553 http://dx.doi.org/10.3389/fncel.2023.1236894 |
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