Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia

Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare interstitial lung disease of unknown cause. It usually responds well to systemic corticosteroid therapy, but relapses are frequent. We describe two cases of 21- and 27-year-old patients, presenting with dyspnea. The diagnosis of steroid-rela...

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Detalles Bibliográficos
Autores principales: Daboussi, Selsabil, Essebaa, Samia, Mhamdi, Samira, Aichaouia, Chiraz, Hela, Ghedira, Ayadi, Aida, Zied, Moetemri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483178/
https://www.ncbi.nlm.nih.gov/pubmed/37691733
http://dx.doi.org/10.12688/f1000research.130939.3
Descripción
Sumario:Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare interstitial lung disease of unknown cause. It usually responds well to systemic corticosteroid therapy, but relapses are frequent. We describe two cases of 21- and 27-year-old patients, presenting with dyspnea. The diagnosis of steroid-relapsing and steroid-dependent ICEP was made respectively. Mepolizumab was prescribed to both patients. This treatment resulted in successful long-term disease management with much fewer side effects than a traditional corticosteroid therapy.

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