Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia

Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare interstitial lung disease of unknown cause. It usually responds well to systemic corticosteroid therapy, but relapses are frequent. We describe two cases of 21- and 27-year-old patients, presenting with dyspnea. The diagnosis of steroid-rela...

Descripción completa

Detalles Bibliográficos
Autores principales: Daboussi, Selsabil, Essebaa, Samia, Mhamdi, Samira, Aichaouia, Chiraz, Hela, Ghedira, Ayadi, Aida, Zied, Moetemri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483178/
https://www.ncbi.nlm.nih.gov/pubmed/37691733
http://dx.doi.org/10.12688/f1000research.130939.3
_version_ 1785102324381777920
author Daboussi, Selsabil
Essebaa, Samia
Mhamdi, Samira
Aichaouia, Chiraz
Hela, Ghedira
Ayadi, Aida
Zied, Moetemri
author_facet Daboussi, Selsabil
Essebaa, Samia
Mhamdi, Samira
Aichaouia, Chiraz
Hela, Ghedira
Ayadi, Aida
Zied, Moetemri
author_sort Daboussi, Selsabil
collection PubMed
description Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare interstitial lung disease of unknown cause. It usually responds well to systemic corticosteroid therapy, but relapses are frequent. We describe two cases of 21- and 27-year-old patients, presenting with dyspnea. The diagnosis of steroid-relapsing and steroid-dependent ICEP was made respectively. Mepolizumab was prescribed to both patients. This treatment resulted in successful long-term disease management with much fewer side effects than a traditional corticosteroid therapy.
format Online
Article
Text
id pubmed-10483178
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher F1000 Research Limited
record_format MEDLINE/PubMed
spelling pubmed-104831782023-09-08 Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia Daboussi, Selsabil Essebaa, Samia Mhamdi, Samira Aichaouia, Chiraz Hela, Ghedira Ayadi, Aida Zied, Moetemri F1000Res Case Report Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare interstitial lung disease of unknown cause. It usually responds well to systemic corticosteroid therapy, but relapses are frequent. We describe two cases of 21- and 27-year-old patients, presenting with dyspnea. The diagnosis of steroid-relapsing and steroid-dependent ICEP was made respectively. Mepolizumab was prescribed to both patients. This treatment resulted in successful long-term disease management with much fewer side effects than a traditional corticosteroid therapy. F1000 Research Limited 2023-09-05 /pmc/articles/PMC10483178/ /pubmed/37691733 http://dx.doi.org/10.12688/f1000research.130939.3 Text en Copyright: © 2023 Daboussi S et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Daboussi, Selsabil
Essebaa, Samia
Mhamdi, Samira
Aichaouia, Chiraz
Hela, Ghedira
Ayadi, Aida
Zied, Moetemri
Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia
title Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia
title_full Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia
title_fullStr Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia
title_full_unstemmed Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia
title_short Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia
title_sort case report: mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483178/
https://www.ncbi.nlm.nih.gov/pubmed/37691733
http://dx.doi.org/10.12688/f1000research.130939.3
work_keys_str_mv AT daboussiselsabil casereportmepolizumabinthetreatmentofidiopathicchroniceosinophilicpneumonia
AT essebaasamia casereportmepolizumabinthetreatmentofidiopathicchroniceosinophilicpneumonia
AT mhamdisamira casereportmepolizumabinthetreatmentofidiopathicchroniceosinophilicpneumonia
AT aichaouiachiraz casereportmepolizumabinthetreatmentofidiopathicchroniceosinophilicpneumonia
AT helaghedira casereportmepolizumabinthetreatmentofidiopathicchroniceosinophilicpneumonia
AT ayadiaida casereportmepolizumabinthetreatmentofidiopathicchroniceosinophilicpneumonia
AT ziedmoetemri casereportmepolizumabinthetreatmentofidiopathicchroniceosinophilicpneumonia

Ejemplares similares