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Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools

BACKGROUND: We sought to develop a proteomics-based risk model for lung cancer and evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (PLCOm2012) and a commercially available autoantibody biomarker test. METHODS: We designed a case-control study nested in 6 pr...

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Detalles Bibliográficos
Autores principales: Feng, Xiaoshuang, Wu, Wendy Yi-Ying, Onwuka, Justina Ucheojor, Haider, Zahra, Alcala, Karine, Smith-Byrne, Karl, Zahed, Hana, Guida, Florence, Wang, Renwei, Bassett, Julie K, Stevens, Victoria, Wang, Ying, Weinstein, Stephanie, Freedman, Neal D, Chen, Chu, Tinker, Lesley, Nøst, Therese Haugdahl, Koh, Woon-Puay, Muller, David, Colorado-Yohar, Sandra M, Tumino, Rosario, Hung, Rayjean J, Amos, Christopher I, Lin, Xihong, Zhang, Xuehong, Arslan, Alan A, Sánchez, Maria-Jose, Sørgjerd, Elin Pettersen, Severi, Gianluca, Hveem, Kristian, Brennan, Paul, Langhammer, Arnulf, Milne, Roger L, Yuan, Jian-Min, Melin, Beatrice, Johansson, Mikael, Robbins, Hilary A, Johansson, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483263/
https://www.ncbi.nlm.nih.gov/pubmed/37260165
http://dx.doi.org/10.1093/jnci/djad071