Pax transactivation domain-interacting protein is required for preserving hematopoietic stem cell quiescence via regulating lysosomal activity

Hematopoietic stem cells (HSC) maintain lifetime whole blood hematopoiesis through self-renewal and differentiation. In order to sustain HSC stemness, most HSC reside in a quiescence state, which is affected by diverse cellular stress and intracellular signal transduction. How HSC accommodate those...

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Detalles Bibliográficos
Autores principales: Zhang, Tong, Cui, Manman, Li, Yashu, Cheng, Ying, Gao, Zhuying, Wang, Jing, Zhang, Tiantian, Han, Guoqiang, Yin, Rong, Wang, Peipei, Tian, Wen, Liu, Weidong, Hu, Jin, Wang, Yuhua, Liu, Zheming, Zhang, Haojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Article - Hematopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483346/
https://www.ncbi.nlm.nih.gov/pubmed/36924252
http://dx.doi.org/10.3324/haematol.2022.282224

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