Myeloid cells from Langerhans cell histiocytosis patients exhibit increased vesicle trafficking and an altered secretome capable of activating NK cells

Langerhans cell histiocytosis (LCH) is a potentially life-threatening inflammatory myeloid neoplasia linked to pediatric neurodegeneration, whereby transformed LCH cells form agglomerated lesions in various organs. Although MAP-kinase pathway mutations have been identified in LCH cells, the function...

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Detalles Bibliográficos
Autores principales: Hagey, Daniel W., Kvedaraite, Egle, Akber, Mira, Görgens, André, Javadi, Joman, von Bahr Greenwood, Tatiana, Björklund, Caroline, Åkefeldt, Selma Olsson, Hannegård-Hamrin, Tova, Arnell, Henrik, Dobra, Katalin, Herold, Nikolas, Svensson, Mattias, El Andaloussi, Samir, Henter, Jan-Inge, Lourda, Magda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Article - Hematopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483349/
https://www.ncbi.nlm.nih.gov/pubmed/36924254
http://dx.doi.org/10.3324/haematol.2022.282638

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