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A multi-threaded approach to genotype pattern mining for detecting digenic disease genes

To locate disease-causing DNA variants on the human gene map, the customary approach has been to carry out a genome-wide association study for one variant after another by testing for genotype frequency differences between individuals affected and unaffected with disease. So-called digenic traits ar...

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Detalles Bibliográficos
Autores principales: Zhang, Qingrun, Bhatia, Muskan, Park, Taesung, Ott, Jurg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483394/
https://www.ncbi.nlm.nih.gov/pubmed/37693313
http://dx.doi.org/10.3389/fgene.2023.1222517