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ANGPTL2+cancer-associated fibroblasts and SPP1+macrophages are metastasis accelerators of colorectal cancer

BACKGROUND: Liver metastasis (LM) is a leading cause of cancer-related deaths in CRC patients, whereas the associated mechanisms have not yet been fully elucidated. Therefore, it is urgently needed to deeply explore novel metastasis accelerators and therapeutic targets of LM-CRC. METHODS: The bulk R...

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Detalles Bibliográficos
Autores principales: Liu, Xiangxiang, Qin, Jian, Nie, Junjie, Gao, Rui, Hu, Shangshang, Sun, Huiling, Wang, Shukui, Pan, Yuqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483401/
https://www.ncbi.nlm.nih.gov/pubmed/37691929
http://dx.doi.org/10.3389/fimmu.2023.1185208