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The Effect of Burns on Children’s Growth Trajectory: A Nationwide Cohort Study

This study evaluates the short- and long-term effect of burns on children’s height and weight, by comparing their pre and postburn growth trajectory. We invited children (≤17 years old), who sustained a burn requiring surgical treatment or admission at one of the Dutch burn centers in 2013 (n = 175)...

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Autores principales: Cuijpers, Maxime D, van de Sande, Pauline J H, Cords, Charlotte I, Scholten-Jaegers, Sonja M H J, van Zuijlen, Paul P M, Baartmans, Martin G A, Pijpe, Anouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483463/
https://www.ncbi.nlm.nih.gov/pubmed/36728628
http://dx.doi.org/10.1093/jbcr/irad013
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author Cuijpers, Maxime D
van de Sande, Pauline J H
Cords, Charlotte I
Scholten-Jaegers, Sonja M H J
van Zuijlen, Paul P M
Baartmans, Martin G A
Pijpe, Anouk
author_facet Cuijpers, Maxime D
van de Sande, Pauline J H
Cords, Charlotte I
Scholten-Jaegers, Sonja M H J
van Zuijlen, Paul P M
Baartmans, Martin G A
Pijpe, Anouk
author_sort Cuijpers, Maxime D
collection PubMed
description This study evaluates the short- and long-term effect of burns on children’s height and weight, by comparing their pre and postburn growth trajectory. We invited children (≤17 years old), who sustained a burn requiring surgical treatment or admission at one of the Dutch burn centers in 2013 (n = 175). As well as children who sustained a severe burn, covering >10% of the total body surface area (TBSA), throughout 2009–2018 (n = 228). Data was collected from a survey on health-related topics, Youth Health Care records, and the Dutch Burn Repository R3. For all participants, height and weight were converted to Z-scores using Dutch reference values. Linear mixed modeling, nested on the individual level, was used to examine the associations between burns and children’s height and weight Z-scores. Children’s height and weight Z-scores remained within the normal range throughout the study period. During the first-year postburn, children’s height and weight Z-scores decreased by −0.21 (95% CI −0.41, −0.01) and −0.23 (95% CI −0.46, −0.04), respectively. Beyond the first-year postburn, estimates were consistent with a positive linear association between burn size and the overall effect of burns on participants’ height and weight Z-scores. This included a modest, but statistically significant, effect among participants with a burn covering ≤4.5% and >14.0% of the TBSA. Sensitivity analyses did not alter our findings. In conclusion, children were on track or even surpassed their growth potential. Our findings could therefore be considered reassuring to patients, parents, and clinicians.
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spelling pubmed-104834632023-09-08 The Effect of Burns on Children’s Growth Trajectory: A Nationwide Cohort Study Cuijpers, Maxime D van de Sande, Pauline J H Cords, Charlotte I Scholten-Jaegers, Sonja M H J van Zuijlen, Paul P M Baartmans, Martin G A Pijpe, Anouk J Burn Care Res Original Articles This study evaluates the short- and long-term effect of burns on children’s height and weight, by comparing their pre and postburn growth trajectory. We invited children (≤17 years old), who sustained a burn requiring surgical treatment or admission at one of the Dutch burn centers in 2013 (n = 175). As well as children who sustained a severe burn, covering >10% of the total body surface area (TBSA), throughout 2009–2018 (n = 228). Data was collected from a survey on health-related topics, Youth Health Care records, and the Dutch Burn Repository R3. For all participants, height and weight were converted to Z-scores using Dutch reference values. Linear mixed modeling, nested on the individual level, was used to examine the associations between burns and children’s height and weight Z-scores. Children’s height and weight Z-scores remained within the normal range throughout the study period. During the first-year postburn, children’s height and weight Z-scores decreased by −0.21 (95% CI −0.41, −0.01) and −0.23 (95% CI −0.46, −0.04), respectively. Beyond the first-year postburn, estimates were consistent with a positive linear association between burn size and the overall effect of burns on participants’ height and weight Z-scores. This included a modest, but statistically significant, effect among participants with a burn covering ≤4.5% and >14.0% of the TBSA. Sensitivity analyses did not alter our findings. In conclusion, children were on track or even surpassed their growth potential. Our findings could therefore be considered reassuring to patients, parents, and clinicians. Oxford University Press 2023-02-02 /pmc/articles/PMC10483463/ /pubmed/36728628 http://dx.doi.org/10.1093/jbcr/irad013 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of the American Burn Association. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Articles
Cuijpers, Maxime D
van de Sande, Pauline J H
Cords, Charlotte I
Scholten-Jaegers, Sonja M H J
van Zuijlen, Paul P M
Baartmans, Martin G A
Pijpe, Anouk
The Effect of Burns on Children’s Growth Trajectory: A Nationwide Cohort Study
title The Effect of Burns on Children’s Growth Trajectory: A Nationwide Cohort Study
title_full The Effect of Burns on Children’s Growth Trajectory: A Nationwide Cohort Study
title_fullStr The Effect of Burns on Children’s Growth Trajectory: A Nationwide Cohort Study
title_full_unstemmed The Effect of Burns on Children’s Growth Trajectory: A Nationwide Cohort Study
title_short The Effect of Burns on Children’s Growth Trajectory: A Nationwide Cohort Study
title_sort effect of burns on children’s growth trajectory: a nationwide cohort study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483463/
https://www.ncbi.nlm.nih.gov/pubmed/36728628
http://dx.doi.org/10.1093/jbcr/irad013
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