Cargando…

Synthesis, Structural Investigations, DNA/BSA Interactions, Molecular Docking Studies, and Anticancer Activity of a New 1,4-Disubstituted 1,2,3-Triazole Derivative

[Image: see text] We report herein a new 1,2,3-triazole derivative, namely, 4-((1-(3,4-dichlorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-2-hydroxybenzaldehyde, which was synthesized by copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC). The structure of the compound was analyzed using Fourier trans...

Descripción completa

Detalles Bibliográficos
Autores principales:	Göktürk, Tolga, Sakallı Çetin, Esin, Hökelek, Tuncer, Pekel, Hanife, Şensoy, Özge, Aksu, Ebru Nur, Güp, Ramazan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483525/ https://www.ncbi.nlm.nih.gov/pubmed/37692230 http://dx.doi.org/10.1021/acsomega.3c03355

Ejemplares similares

Regioselective Synthesis and Molecular Docking Studies of 1,5-Disubstituted 1,2,3-Triazole Derivatives of Pyrimidine Nucleobases
por: Algieri, Vincenzo, et al.
Publicado: (2022)

Synthesis of 2-tetrafluoropyridyl-4,5-disubstituted 1,2,3-triazoles
por: Beyki, Khalil, et al.
Publicado: (2016)

Synthesis, antibacterial activity and molecular docking study of vanillin derived 1,4-disubstituted 1,2,3-triazoles as inhibitors of bacterial DNA synthesis
por: Hussain, Mumtaz, et al.
Publicado: (2019)

Synthesis of Chiral 1,4-Disubstituted-1,2,3-Triazole Derivatives from Amino Acids
por: Klein, Michael, et al.
Publicado: (2009)

Synthesis, Structure and In Vitro Cytotoxic Activity of Novel Cinchona—Chalcone Hybrids with 1,4-Disubstituted- and 1,5-Disubstituted 1,2,3-Triazole Linkers
por: Jernei, Tamás, et al.
Publicado: (2019)

1,4-Disubstituted 1,2,3-Triazoles as Amide Bond Surrogates for the Stabilisation of Linear Peptides with Biological Activity
por: Rečnik, Lisa-Maria, et al.
Publicado: (2020)

Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitors
por: Jiang, Xiangyi, et al.
Publicado: (2019)

Dimethyl sulfoxide reduces the stability but enhances catalytic activity of the main SARS‐CoV‐2 protease 3CLpro
por: Ferreira, Juliana C., et al.
Publicado: (2021)

1,4-Disubstituted 1H-1,2,3-Triazoles for Renal Diseases: Studies of Viability, Anti-Inflammatory, and Antioxidant Activities
por: Cheng, Ching-Yi, et al.
Publicado: (2020)

A Green Ultrasound Synthesis, Characterization and Antibacterial Evaluation of 1,4-Disubstituted 1,2,3-Triazoles Tethering Bioactive Benzothiazole Nucleus
por: Rezki, Nadjet
Publicado: (2016)

1,4-Disubstituted 1H-1,2,3-Triazole Containing Peptidotriazolamers: A New Class of Peptidomimetics With Interesting Foldamer Properties
por: Schröder, David C., et al.
Publicado: (2019)

Synthesis and Antiviral Evaluation of (1,4-Disubstituted-1,2,3-Triazol)-(E)-2-Methyl-but-2-Enyl Nucleoside Phosphonate Prodrugs
por: Abuduaini, Tuniyazi, et al.
Publicado: (2021)

Synthesis of N-perfluoroalkyl-3,4-disubstituted pyrroles by rhodium-catalyzed transannulation of N-fluoroalkyl-1,2,3-triazoles with terminal alkynes
por: Bakhanovich, Olga, et al.
Publicado: (2021)

Natural phosphate-supported Cu(ii), an efficient and recyclable catalyst for the synthesis of xanthene and 1,4-disubstituted-1,2,3-triazole derivatives
por: Amini, Abbas, et al.
Publicado: (2018)

1,2,3-Triazoles
por: Rachwal, S., et al.
Publicado: (2008)

New 1,2,3-Triazole-Appended Bis-pyrazoles: Synthesis, Bioevaluation, and Molecular Docking
por: Danne, Ashruba B., et al.
Publicado: (2021)

Synthesis, antimicrobial evaluation and docking studies of fluorinated imine linked 1,2,3-triazoles
por: Kumar, Aman, et al.
Publicado: (2022)

Copper(I)-catalyzed tandem reaction: synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and alkynes
por: Israr, Muhammad, et al.
Publicado: (2018)

1,4-Disubstituted-1,2,3-Triazole Compounds Induce Ultrastructural Alterations in Leishmania amazonensis Promastigote: An in Vitro Antileishmanial and in Silico Pharmacokinetic Study
por: Almeida-Souza, Fernando, et al.
Publicado: (2020)

Crystal structure and Hirshfeld surface analysis of 1-[(1-butyl-1H-1,2,3-triazol-4-yl)methyl]-3-methylquinoxalin-2(1H)-one
por: Abad, Nadeem, et al.
Publicado: (2018)

Efficient stabilisation of a dihydrogenphosphate tetramer and a dihydrogenpyrophosphate dimer by a cyclic pseudopeptide containing 1,4-disubstituted 1,2,3-triazole moieties
por: Mungalpara, Disha, et al.
Publicado: (2017)

Copper-catalyzed in situ oxidative-coupling for one-pot synthesis of 5-aryl-1,4-disubstituted 1,2,3-triazoles under mild conditions
por: Wang, Chao, et al.
Publicado: (2021)

Synthesis of Dense 1,2,3-Triazole Oligomers Consisting Preferentially of 1,5-Disubstituted Units via Ruthenium(II)-Catalyzed Azide–Alkyne Cycloaddition
por: Taguchi, Ryoichi, et al.
Publicado: (2023)

Tyrosol Derivatives, Bearing 3,5-Disubstituted Isoxazole and 1,4-Disubstituted Triazole, as Potential Antileukemia Agents by Promoting Apoptosis
por: Abdelkafi-Koubaa, Zaineb, et al.
Publicado: (2022)

Late Postoperative Evaluation of Retinal and Choroidal Thickness and Retinal Vessel Caliber after Surgical Repair of Corneal Perforation
por: Pekel, Gökhan, et al.
Publicado: (2015)

4,5-Disubstituted 1,2,3-triazoles: Effective Inhibition of Indoleamine 2,3-Dioxygenase 1 Enzyme Regulates T cell Activity and Mitigates Tumor Growth
por: Panda, Subhankar, et al.
Publicado: (2019)

Proliferation, Migration and Invasion of Breast Cancer Cell Lines Are Inhibited by 1,5-Disubstituted Tetrazol-1,2,3-triazole Hybrids through Interaction with p53
por: Moreno-Perea, Marisol, et al.
Publicado: (2023)

Antibacterial Activities and Molecular Docking of Novel Sulfone Biscompound Containing Bioactive 1,2,3-Triazole Moiety
por: Rashdan, Huda R. M., et al.
Publicado: (2021)

Synthesis, in silico ADME, molecular docking and in vitro cytotoxicity evaluation of stilbene linked 1,2,3-triazoles
por: Das, Arnika, et al.
Publicado: (2021)

A Simple Work-Up-free, Solvent-free Approach to Novel Amino Acid Linked 1,4-Disubstituted 1,2,3-Triazoles as Potent Antituberculosis Agents
por: Garg, Anirban, et al.
Publicado: (2020)

Synthesis of a novel resorcin[4]arene–glucose conjugate and its catalysis of the CuAAC reaction for the synthesis of 1,4-disubstituted 1,2,3-triazoles in water
por: Husain, Ali A., et al.
Publicado: (2019)

Crystal structure and Hirshfeld surface analysis of ethyl 2-{4-[(3-methyl-2-oxo-1,2-dihydroquinoxalin-1-yl)methyl]-1H-1,2,3-triazol-1-yl}acetate
por: Abad, Nadeem, et al.
Publicado: (2018)

Microwave-assisted synthesis, biological evaluation and molecular docking studies of new coumarin-based 1,2,3-triazoles
por: Dharavath, Ravinder, et al.
Publicado: (2020)

Novel 1,2,3-Triazole-Based Benzothiazole Derivatives: Efficient Synthesis, DFT, Molecular Docking, and ADMET Studies
por: Mirjafary, Zohreh, et al.
Publicado: (2022)

A One-Pot Six-Component Reaction for the Synthesis of 1,5-Disubstituted Tetrazol-1,2,3-Triazole Hybrids and Their Cytotoxic Activity against the MCF-7 Cell Line
por: Aguilar-Morales, Cesia M., et al.
Publicado: (2021)

1,2,3-Triazoles as Biomimetics in Peptide Science
por: Agouram, Naima, et al.
Publicado: (2021)

1-Phenyl-2-(1H-1,2,4-triazol-1-yl)ethanone
por: Özel Güven, Özden, et al.
Publicado: (2008)

1-Phenyl-2-(1H-1,2,4-triazol-1-yl)ethanol
por: Özel Güven, Özden, et al.
Publicado: (2008)

Crystal structure, Hirshfeld surface analysis, interaction energy and DFT studies of 4-[(4-allyl-2-methoxyphenoxy)methyl]-1-(4-methoxyphenyl)-1H-1,2,3-triazole
por: Taia, Abdelmaoujoud, et al.
Publicado: (2020)

Does Fundus Fluorescein Angiography Procedure Affect Ocular Pulse Amplitude?
por: Pekel, Gökhan, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_hrdiogu2ed0tnv3ksqadtrv7lk