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2-[5-(2,3-Dimethoxynaphthalen-1-yl)-4,5-dihydro-1H-pyrazol-3-yl]-3-methoxyphenol
In the title compound, C(22)H(22)N(2)O(4), the central pyrazoline ring exhibits a nearly planar structure (r.m.s. deviation = 0.025 Å) despite having two sp (3) carbon atoms. The pyrazoline ring subtends dihedral angles of 4.61 (1) and 87.31 (1)° with the pendant benzene ring and naphthalene ring sy...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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International Union of Crystallography
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483541/ https://www.ncbi.nlm.nih.gov/pubmed/37693784 http://dx.doi.org/10.1107/S2414314623006685 |
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author | Sung, Jiha |
author_facet | Sung, Jiha |
author_sort | Sung, Jiha |
collection | PubMed |
description | In the title compound, C(22)H(22)N(2)O(4), the central pyrazoline ring exhibits a nearly planar structure (r.m.s. deviation = 0.025 Å) despite having two sp (3) carbon atoms. The pyrazoline ring subtends dihedral angles of 4.61 (1) and 87.31 (1)° with the pendant benzene ring and naphthalene ring system, respectively. The dihedral angle between the planes of the benzene ring and the naphthalene ring system is 89.76 (2)°. An intramolecular O—H⋯N hydrogen bond forms an S(6) ring motif. In the crystal, inversion dimers formed by pairwise weak N—H⋯N hydrogen bonds generate R (2) (2)(4) loops and the dimers are linked by pairwise C—H⋯O hydrogen bonds [which generate R (2) (2)(8) loops] into [100] chains. [Image: see text] |
format | Online Article Text |
id | pubmed-10483541 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-104835412023-09-08 2-[5-(2,3-Dimethoxynaphthalen-1-yl)-4,5-dihydro-1H-pyrazol-3-yl]-3-methoxyphenol Sung, Jiha IUCrdata Data Reports In the title compound, C(22)H(22)N(2)O(4), the central pyrazoline ring exhibits a nearly planar structure (r.m.s. deviation = 0.025 Å) despite having two sp (3) carbon atoms. The pyrazoline ring subtends dihedral angles of 4.61 (1) and 87.31 (1)° with the pendant benzene ring and naphthalene ring system, respectively. The dihedral angle between the planes of the benzene ring and the naphthalene ring system is 89.76 (2)°. An intramolecular O—H⋯N hydrogen bond forms an S(6) ring motif. In the crystal, inversion dimers formed by pairwise weak N—H⋯N hydrogen bonds generate R (2) (2)(4) loops and the dimers are linked by pairwise C—H⋯O hydrogen bonds [which generate R (2) (2)(8) loops] into [100] chains. [Image: see text] International Union of Crystallography 2023-08-10 /pmc/articles/PMC10483541/ /pubmed/37693784 http://dx.doi.org/10.1107/S2414314623006685 Text en © Jiha Sung 2023 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Data Reports Sung, Jiha 2-[5-(2,3-Dimethoxynaphthalen-1-yl)-4,5-dihydro-1H-pyrazol-3-yl]-3-methoxyphenol |
title | 2-[5-(2,3-Dimethoxynaphthalen-1-yl)-4,5-dihydro-1H-pyrazol-3-yl]-3-methoxyphenol |
title_full | 2-[5-(2,3-Dimethoxynaphthalen-1-yl)-4,5-dihydro-1H-pyrazol-3-yl]-3-methoxyphenol |
title_fullStr | 2-[5-(2,3-Dimethoxynaphthalen-1-yl)-4,5-dihydro-1H-pyrazol-3-yl]-3-methoxyphenol |
title_full_unstemmed | 2-[5-(2,3-Dimethoxynaphthalen-1-yl)-4,5-dihydro-1H-pyrazol-3-yl]-3-methoxyphenol |
title_short | 2-[5-(2,3-Dimethoxynaphthalen-1-yl)-4,5-dihydro-1H-pyrazol-3-yl]-3-methoxyphenol |
title_sort | 2-[5-(2,3-dimethoxynaphthalen-1-yl)-4,5-dihydro-1h-pyrazol-3-yl]-3-methoxyphenol |
topic | Data Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483541/ https://www.ncbi.nlm.nih.gov/pubmed/37693784 http://dx.doi.org/10.1107/S2414314623006685 |
work_keys_str_mv | AT sungjiha 2523dimethoxynaphthalen1yl45dihydro1hpyrazol3yl3methoxyphenol |