The LIN28B–let‐7–PBK pathway is essential for group 3 medulloblastoma tumor growth and survival

Children with Group 3 medulloblastoma (G3 MB) have a very poor prognosis, and many do not survive beyond 5 years after diagnosis. A factor that may contribute to this is the lack of available targeted therapy. Expression of protein lin‐28 homolog B (LIN28B), a regulator of developmental timing, is u...

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Detalles Bibliográficos
Autores principales: Shahab, Shubin W., Roggeveen, Christianna M., Sun, Jiarong, Kunhiraman, Haritha, McSwain, Leon F., Juraschka, Kyle, Kumar, Sachin A., Saulnier, Olivier, Taylor, Michael D., Schniederjan, Matthew, Schnepp, Robert W., MacDonald, Tobey J, Kenney, Anna Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483609/
https://www.ncbi.nlm.nih.gov/pubmed/37341142
http://dx.doi.org/10.1002/1878-0261.13477

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