Differential second messenger signaling via dopamine neurons bidirectionally regulates memory retention

Memory formation and forgetting unnecessary memory must be balanced for adaptive animal behavior. While cyclic AMP (cAMP) signaling via dopamine neurons induces memory formation, here we report that cyclic guanine monophosphate (cGMP) signaling via dopamine neurons launches forgetting of unconsolida...

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Detalles Bibliográficos
Autores principales: Takakura, Mai, Lam, Yu Hong, Nakagawa, Reiko, Ng, Man Yung, Hu, Xinyue, Bhargava, Priyanshu, Alia, Abdalla G., Gu, Yuzhe, Wang, Zigao, Ota, Takeshi, Kimura, Yoko, Morimoto, Nao, Osakada, Fumitaka, Lee, Ah Young, Leung, Danny, Miyashita, Tomoyuki, Du, Juan, Okuno, Hiroyuki, Hirano, Yukinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483633/
https://www.ncbi.nlm.nih.gov/pubmed/37639608
http://dx.doi.org/10.1073/pnas.2304851120

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