5-Methoxyisatin N(4)-Pyrrolidinyl Thiosemicarbazone (MeOIstPyrd) Restores Mutant p53 and Inhibits the Growth of Skin Cancer Cells, In Vitro

[Image: see text] A series of novel thiosemicarbazone derivatives containing 5-methoxy isatin were designed and synthesized with modification on N(4) position. Derivatives considering structure–activity relationship have been designed and synthesized by condensing thiosemicarbazide with 5-methoxy is...

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Autores principales: Shahi, Nerina, Yadav, Paras Nath, Chaudhary, Upendra, Saad, Mohd, Mahiya, Kuldeep, Khan, Arif, Shafi, Syed, Pokharel, Yuba Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483675/
https://www.ncbi.nlm.nih.gov/pubmed/37692215
http://dx.doi.org/10.1021/acsomega.3c03824

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