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CUL4B-DDB1-COP1-mediated UTX downregulation promotes colorectal cancer progression

BACKGROUND: UTX (encoded by KDM6A), a histone demethylase for H3K27me2/3, is frequently mutated in human cancers. However, its functional and regulatory mechanisms in colorectal cancer (CRC) remain unclear. METHODS: Immunohistochemistry staining was used to investigate the clinical relevance of UTX...

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Detalles Bibliográficos
Autores principales:	Luo, Dakui, Chen, Min, Li, Qingguo, Wang, Kangjunjie, Wang, Kaihua, Li, Junqiang, Fu, Guoxiang, Shan, Zezhi, Liu, Qi, Yang, Yufei, Liang, Lei, Ma, Yanlei, Qin, Yi, Qin, Jun, Gao, Daming, Li, Xinxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483726/ https://www.ncbi.nlm.nih.gov/pubmed/37679762 http://dx.doi.org/10.1186/s40164-023-00440-z

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