A systematic review of randomised controlled trials with adaptive and traditional group sequential designs – applications in cardiovascular clinical trials

BACKGROUND: Trial design plays a key role in clinical trials. Traditional group sequential design has been used in cardiovascular clinical trials over decades as the trials can potentially be stopped early, therefore, it can reduce pre-planned sample size and trial resources. In contrast, trials wit...

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Detalles Bibliográficos
Autores principales: Zhang, Jufen, Saju, Christy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483862/
https://www.ncbi.nlm.nih.gov/pubmed/37679710
http://dx.doi.org/10.1186/s12874-023-02024-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483862/
https://www.ncbi.nlm.nih.gov/pubmed/37679710
http://dx.doi.org/10.1186/s12874-023-02024-1

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