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In silico evaluation of binding interaction and ADME study of new 1,3-diazetidin-2-one derivatives with high antiproliferative activity

A series of eight novels’ 1,3-diazetidin-2-ones have been proposed to assess their potential activities. They are intended to examine antiproliferative effects through inhibition of epidermal growth factor receptor (EGFR) expression. These eight compounds strongly interact with the EGFR protein, res...

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Detalles Bibliográficos
Autores principales:	Abdulredha, Farah Haidar, Mahdi, Monther Faisal, Khan, Ayad Kareem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483897/ https://www.ncbi.nlm.nih.gov/pubmed/37692021 http://dx.doi.org/10.4103/JAPTR.JAPTR_116_23

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