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Leveraging the genetic correlation between traits improves the detection of epistasis in genome-wide association studies

Epistasis, commonly defined as the interaction between genetic loci, is known to play an important role in the phenotypic variation of complex traits. As a result, many statistical methods have been developed to identify genetic variants that are involved in epistasis, and nearly all of these approa...

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Detalles Bibliográficos
Autores principales: Stamp, Julian, DenAdel, Alan, Weinreich, Daniel, Crawford, Lorin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484060/
https://www.ncbi.nlm.nih.gov/pubmed/37243672
http://dx.doi.org/10.1093/g3journal/jkad118