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Leveraging the genetic correlation between traits improves the detection of epistasis in genome-wide association studies
Epistasis, commonly defined as the interaction between genetic loci, is known to play an important role in the phenotypic variation of complex traits. As a result, many statistical methods have been developed to identify genetic variants that are involved in epistasis, and nearly all of these approa...
Autores principales: | Stamp, Julian, DenAdel, Alan, Weinreich, Daniel, Crawford, Lorin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484060/ https://www.ncbi.nlm.nih.gov/pubmed/37243672 http://dx.doi.org/10.1093/g3journal/jkad118 |
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