A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer

The FOXA1 pioneer factor is an essential mediator of steroid receptor function in multiple hormone-dependent cancers, including breast and prostate cancers, enabling nuclear receptors such as estrogen receptor (ER) and androgen receptor (AR) to activate lineage-specific growth programs. FOXA1 is als...

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Detalles Bibliográficos
Autores principales: Dorso, M., Patel, Payal T., Pankov, Aleksandr, Boyer, Jacob A., Soni, Rajesh K., Del Priore, Isabella S., Hayatt, Omar, Kulick, Amanda, Hagen, Connor J., de Stanchina, Elisa, Junttila, Melissa R., Daemen, Anneleen, Friedman, Lori S., Hendrickson, Ronald C., Chandarlapaty, Sarat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484118/
https://www.ncbi.nlm.nih.gov/pubmed/37691854
http://dx.doi.org/10.1158/2767-9764.CRC-23-0310

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