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Comparison of Long-Term Outcomes of Patients With Myocardia Infarction (MI) With Non-obstructive Coronary Arteries and MI With Obstructive Coronary Arteries: A Systematic Review and Meta-Analysis

The aim of this study was to compare long-term outcomes in patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) and patients with myocardial infarction with obstructive coronary arteries (MIOCA). This meta-analysis was conducted according to the recommendations of the...

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Autores principales: Naeem, Muhammad O, Khan, Saad Khalid, Gergess, Ramy R, Addi Palle, Lokeshwar Raaju, Krupanagaram, Santoshi, Khan, Muhammad Waqas, Haseeb, Madiha D, Hirani, Shamsha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484151/
https://www.ncbi.nlm.nih.gov/pubmed/37692745
http://dx.doi.org/10.7759/cureus.43137
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author Naeem, Muhammad O
Khan, Saad Khalid
Gergess, Ramy R
Addi Palle, Lokeshwar Raaju
Krupanagaram, Santoshi
Khan, Muhammad Waqas
Haseeb, Madiha D
Hirani, Shamsha
author_facet Naeem, Muhammad O
Khan, Saad Khalid
Gergess, Ramy R
Addi Palle, Lokeshwar Raaju
Krupanagaram, Santoshi
Khan, Muhammad Waqas
Haseeb, Madiha D
Hirani, Shamsha
author_sort Naeem, Muhammad O
collection PubMed
description The aim of this study was to compare long-term outcomes in patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) and patients with myocardial infarction with obstructive coronary arteries (MIOCA). This meta-analysis was conducted according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The literature search was conducted in online databases including PubMed and Web of Science from 2010 onwards. Primary outcomes assessed in this meta-analysis included major adverse cardiovascular events (MACE) and all-cause mortality. Secondary outcomes included cardiovascular mortality and myocardial infarction. A total of 16 studies were included in the meta-analysis. Pooled analysis showed that the risk of MACE was higher in MIOCA patients (risk ratio (RR): 1.47, 95%CI: 1.43-1.52, p-value: 0.001) compared to MINOCA patients. Additionally, the risk of all-cause mortality was also significantly higher in MIOCA patients compared to MINOCA (RR: 1.33, 95%CI: 1.14-1.56, p-value: 0.001). Our findings also indicate that patients with MIOCA are at a significantly higher risk of recurrent myocardial infarction and cardiovascular-related mortality compared to patients with MINOCA. Overall, the insights gained from this meta-analysis have significant clinical implications, guiding decision-making in the management of patients with MINOCA.
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spelling pubmed-104841512023-09-08 Comparison of Long-Term Outcomes of Patients With Myocardia Infarction (MI) With Non-obstructive Coronary Arteries and MI With Obstructive Coronary Arteries: A Systematic Review and Meta-Analysis Naeem, Muhammad O Khan, Saad Khalid Gergess, Ramy R Addi Palle, Lokeshwar Raaju Krupanagaram, Santoshi Khan, Muhammad Waqas Haseeb, Madiha D Hirani, Shamsha Cureus Cardiac/Thoracic/Vascular Surgery The aim of this study was to compare long-term outcomes in patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) and patients with myocardial infarction with obstructive coronary arteries (MIOCA). This meta-analysis was conducted according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The literature search was conducted in online databases including PubMed and Web of Science from 2010 onwards. Primary outcomes assessed in this meta-analysis included major adverse cardiovascular events (MACE) and all-cause mortality. Secondary outcomes included cardiovascular mortality and myocardial infarction. A total of 16 studies were included in the meta-analysis. Pooled analysis showed that the risk of MACE was higher in MIOCA patients (risk ratio (RR): 1.47, 95%CI: 1.43-1.52, p-value: 0.001) compared to MINOCA patients. Additionally, the risk of all-cause mortality was also significantly higher in MIOCA patients compared to MINOCA (RR: 1.33, 95%CI: 1.14-1.56, p-value: 0.001). Our findings also indicate that patients with MIOCA are at a significantly higher risk of recurrent myocardial infarction and cardiovascular-related mortality compared to patients with MINOCA. Overall, the insights gained from this meta-analysis have significant clinical implications, guiding decision-making in the management of patients with MINOCA. Cureus 2023-08-08 /pmc/articles/PMC10484151/ /pubmed/37692745 http://dx.doi.org/10.7759/cureus.43137 Text en Copyright © 2023, Naeem et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiac/Thoracic/Vascular Surgery
Naeem, Muhammad O
Khan, Saad Khalid
Gergess, Ramy R
Addi Palle, Lokeshwar Raaju
Krupanagaram, Santoshi
Khan, Muhammad Waqas
Haseeb, Madiha D
Hirani, Shamsha
Comparison of Long-Term Outcomes of Patients With Myocardia Infarction (MI) With Non-obstructive Coronary Arteries and MI With Obstructive Coronary Arteries: A Systematic Review and Meta-Analysis
title Comparison of Long-Term Outcomes of Patients With Myocardia Infarction (MI) With Non-obstructive Coronary Arteries and MI With Obstructive Coronary Arteries: A Systematic Review and Meta-Analysis
title_full Comparison of Long-Term Outcomes of Patients With Myocardia Infarction (MI) With Non-obstructive Coronary Arteries and MI With Obstructive Coronary Arteries: A Systematic Review and Meta-Analysis
title_fullStr Comparison of Long-Term Outcomes of Patients With Myocardia Infarction (MI) With Non-obstructive Coronary Arteries and MI With Obstructive Coronary Arteries: A Systematic Review and Meta-Analysis
title_full_unstemmed Comparison of Long-Term Outcomes of Patients With Myocardia Infarction (MI) With Non-obstructive Coronary Arteries and MI With Obstructive Coronary Arteries: A Systematic Review and Meta-Analysis
title_short Comparison of Long-Term Outcomes of Patients With Myocardia Infarction (MI) With Non-obstructive Coronary Arteries and MI With Obstructive Coronary Arteries: A Systematic Review and Meta-Analysis
title_sort comparison of long-term outcomes of patients with myocardia infarction (mi) with non-obstructive coronary arteries and mi with obstructive coronary arteries: a systematic review and meta-analysis
topic Cardiac/Thoracic/Vascular Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484151/
https://www.ncbi.nlm.nih.gov/pubmed/37692745
http://dx.doi.org/10.7759/cureus.43137
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